Info PhD position: Single-molecule imaging of signal processing in live
bacteria Job description The aim of this project is to uncover within living
cells the spatial and stochastic processes that underlie biochemical signalling
at the single-molecule level. We have recently characterized the dynamics of the
signalling network controlling the motility of bacteria by Förster resonance
energy transfer (FRET) experiments in live cells (Mol Syst Biol 6:382, 2010).
While the signal transfer functions obtained by these ensemble-averaged
measurements provide a useful coarse-grained description in considering
functional aspects, many open questions remain on the underlying molecular
mechanisms that are addressable at the single-molecule level
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